Synthesis of Mn(II) Complexes-Carboxymethyl Chitosan Schiff Base Salicylaldehyde and Antibacterial Activity

The development of compounds with a better antibacterial activity is highly needed. One way to achieve this by modifying the structure compound using chitosan as starting material, because its abundant natural source in Indonesia, biodegradable properties, and where free amines are present. This study aims obtain Mn(II) -Carboxymethyl Chitosan Schiff Base-Salicylaldehyde complex increase against Staphylococcus aureus (Gram positive) Escherichia coli negative). Base carboxymethyl chitosan-salicylaldehyde was synthesized from salicylaldehyde. Next, Carboxymethyl Chitosan-Salicylaldehyde complexed MnCl2.4H2O then characterized FTIR, UV-Vis Spectrophotometer, AAS tested for disc diffusion method coli. product Base-salicylaldehyde brownish yellow solid yield 64% (w/w) has (clear zone diameter 11 mm) 13 mm). Complexes-Carboxymethyl black 59% 17